30 Biotech LargeCap Firms

Components Performance/Risk
Period Return
84.4%
Return Rank
Strong
Risk Exposure
Above Average

The Biotechnology Top 30 firms includes the largest biotech firms by market cap > $10bn, listed on the NASDAQ and NYSE stock exchanges

 

Momentum highlights the trend of the average price computed over a week, compared to the monthly price average, and is indicative of the sector's resilience

Share performances can be ranked by selected time frame, from 2 weeks to one year (default), by selection  in the top-right menu

View the Analytics for fundamental ratio details 

The companion theme of 30 Biotech LargeCap Firms is the selection of the Next 50 MidCap Biotech firms

The top 100 Biotech Firms by market cap are also listed

 

The iShares Biotechnology ETF  composed of an extensive list of biotechnology and pharmaceutical equities - is the benchmark of this theme

The biotech selection of the top 30 by market cap is not weighted - assuming one share of each component had been invested at the beginning of the selected period

 

ABIVAX  , a French  clinical-stage biotechnology company, and Praxis Precision Medicines have been set aside because of exceptional out-of-range performance (after repricing in July 2025 and October 2025)

 

Actual performance of , the tracker fund, maybe higher or lower, depending on the weighting and selection decided by the provider

Check the information available on the iShares Biotechnology ETF site or contact your advisor

Theme Components
Name
Ticker
Sector
Industry
Cur. Price
Mkt. Cap
Performance
Momentum
Risk Rank
Risk Contrib
 
Alnylam Pharmaceuticals ALNY Health CareGene Therapies236.0131 B-46.8% Sharp Down Above Average
Arrowhead Pharmaceuticals ARWR Health CareGene Therapies86.7312 B318.8% Weak Up Above Average
Vertex Pharmaceuticals VRTX Health CareGene Therapies547.59139 B40.8% Weak Up Below Average
BeiGene (ADR) ONC Health CareGene Therapies371.9841 B20.5% Strong Up Average Risk
Ionis Pharmaceuticals IONS Health CareGene Therapies62.0410 B48.4% Neutral Average Risk
Amgen AMGN Health CareBiopharmaceuticals443.84239 B60.7% Strong Up Low Risk
Biogen BIIB Health CareBiopharmaceuticals218.1232 B60.0% Weak Up Below Average
BioMarin Pharmaceutical BMRN Health CareBiopharmaceuticals65.0713 B11.2% Strong Up Below Average
Cytokinetics Inc. CYTK Health CareBiopharmaceuticals77.099.5 B108.3% Weak Down Above Average
Gilead Sciences GILD Health CareBiopharmaceuticals146.74182 B33.9% Weak Up Low Risk
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