30 Biotech LargeCap Firms

Components Performance/Risk
Period Return
57.1%
Return Rank
Strong
Risk Exposure
Above Average

The Biotechnology Top 30 firms includes the largest biotech firms by market cap > $10bn, listed on the NASDAQ and NYSE stock exchanges

 

Momentum highlights the trend of the average price computed over a week, compared to the monthly price average, and is indicative of the sector's resilience

Share performances can be ranked by selected time frame, from 2 weeks to one year (default), by selection  in the top-right menu

View the Analytics for fundamental ratio details 

The companion theme of 30 Biotech LargeCap Firms is the selection of the Next 50 MidCap Biotech firms

The top 100 Biotech Firms by market cap are also listed

 

The iShares Biotechnology ETF  composed of an extensive list of biotechnology and pharmaceutical equities - is the benchmark of this theme

The biotech selection of the top 30 by market cap is not weighted - assuming one share of each component had been invested at the beginning of the selected period

 

ABIVAX  , a French  clinical-stage biotechnology company, and Praxis Precision Medicines have been set aside because of exceptional out-of-range performance (after repricing in July 2025 and October 2025)

 

Actual performance of , the tracker fund, maybe higher or lower, depending on the weighting and selection decided by the provider

Check the information available on the iShares Biotechnology ETF site or contact your advisor

Theme Components
Name
Ticker
Sector
Industry
Cur. Price
Mkt. Cap
Performance
Momentum
Risk Rank
Risk Contrib
 
Alnylam Pharmaceuticals ALNY Health CareGene Therapies223.8230 B-52.3% Weak Down Above Average
Arrowhead Pharmaceuticals ARWR Health CareGene Therapies58.138.1 B61.7% Sharp Down Above Average
Vertex Pharmaceuticals VRTX Health CareGene Therapies485.22123 B17.7% Neutral Below Average
BeiGene (ADR) ONC Health CareGene Therapies349.0839 B8.8% Neutral Below Average
Ionis Pharmaceuticals IONS Health CareGene Therapies42.387.0 B-40.6% Sharp Down Below Average
Amgen AMGN Health CareBiopharmaceuticals412.84223 B47.0% Neutral Below Average
Biogen BIIB Health CareBiopharmaceuticals228.9034 B57.5% Neutral Below Average
BioMarin Pharmaceutical BMRN Health CareBiopharmaceuticals54.3810 B3.6% Weak Down Below Average
Cytokinetics Inc. CYTK Health CareBiopharmaceuticals61.627.6 B1.0% Sharp Down Average Risk
Gilead Sciences GILD Health CareBiopharmaceuticals147.92184 B29.2% Neutral Low Risk
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